The symptoms get better when your baby has been born. It does not involve a rash. Obstetric cholestasis has also been found to run in some families. Facts verified by Dr Andrew Zuschmann. Search Australia's largest database for free in your area, 'It's a heavy burden': Couple's heartbreaking baby name dilemma, The first trimester: 1 - 12 weeks pregnant, Play to thrive! A blood test should be arranged, however, if the itching is continuous and not caused by a rash. 4 It may also occur on other parts of the body such as the face, back and breasts. Right Upper Quadrant (RUQ) pain. You might also have liver function tests to make sure there are no other causes of liver problems, such as hepatitis. The signs of obstetric cholestasis usually develop around the end of the second trimester, although the disorder can develop earlier in pregnancy. Obstetric cholestasis usually begins in the final trimester in the last 10 weeks of pregnancy, although it can begin earlier. Itching, particularly on the hands and feet (often is the only symptom noticed) Often itching is the ONLY symptom noticed by a woman who suffers from ICP. Lysophosphatidic acid is what causes the itching. Women in certain parts of the world are also more likely to have obstetric cholestasis. Due to this increased risk, many care providers will recommend labour induction at 37 weeks. However, I wanted to point out that Urso does NOT treat the itching. Itching is usually worse at night. Cholestasis of pregnancy, also known as obstetric cholestasis or intrahepatic cholestasis of pregnancy, can cause severe itching, especially on the hands and feet. Besides intense itching on your feet and hands, less common symptoms can include: Yellowing of the skin and eyes (jaundice) Nausea; Vomiting; Dark urine; Liver enlargement and abdominal distension (an outward belly extension that's noticeably beyond your normal baby bump) ICP needs medical attention. Perform a physical exam 3. Often the palms of the hands and soles of the feet are the worst affected. Ask questions about your symptoms and medical history 2. The main symptom of cholestasis of pregnancy is severe itching (pruritus). Symptoms of Cholestasis Skin itching, which can become very severe, particularly during the third trimester or during late pregnancy. (Positive Test), How To Conceive A Boy – 6 Expert Tips to Have A Baby Boy, How To Conceive A Girl – 9 Tips To Conceive A Baby Girl, Cervix Dilation – 7 Signs You’re Dilating, Mild jaundice (yellowing of skin, dark urine and pale stools). Obstetric cholestasis is a multifactorial condition of pregnancy characterised by pruritus in the absence of a skin rash with abnormal liver function tests (LFTs), neither of which has an alternative cause and both of which resolve after birth. One theory is the increased levels of bile acid cause irregular heart rates in unborn babies, leading to higher risk of fetal distress, premature birth, and stillbirth. In South America up to 1 in 20 women will develop the condition. However, jaundice is rare, affecting less than 10% of women with ICP. Normally, the liver produces bile, which then flows down the bile ducts into the intestines, where it helps with food digestion. Obstetric cholestasis is a disorder that affects your liver during pregnancy. What is Obstetric Cholestasis? The effects of obstetric cholestasis should subside immediately or not long after the birth of your baby. Â. You don't get a skin rash but you may get marks on your skin from where you have scratched. Keep in mind that itching is very common in pregnancy, due to the stretching of the skin and the extra production of oestrogen, so it is normal to be a little itchy. Drinking water can also help to flush out toxins. Doctors may prescribe ursodeoxycholic acid â this boosts liver function and diminishes the itching. Obstetric cholestasis can affect your absorption of vitamin K, which is important for healthy blood clotting. The itch, which is not associated with a rash, can also spread to the limb extremities e.g. This is also to check that obstetric cholestasis was in fact the correct diagnosis and will help you be aware for future pregnancies. In some cases the itch develops a week or two before the blood levels change. The itching usually occurs on the palms of the hands and the soles of the feet, but it can affect other areas of the body. Obstetric cholestasis occurs in about 1 in 100 pregnancies in the UK and Australia, and is more common in women who are pregnant with multiples. This pregnancy related condition can be potentially very serious, so it’s important to know as much about it as possible. It most often goes away within a few days after delivery. This causes itching and yellowing of your skin, eyes, and mucous membranes (jaundice). Steroids are also sometimes used, but arenât as safe. 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